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Salzmann's nodulaire degeneratie

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Salzmann’s nodular degeneration is a slowly progressive condition in which greyish-white to bluish thickenings are seen at the front of the cornea (in front of Bowman’s layer). The thickenings usually occur on both eyes and can be located near the limbus or in the mid-periphery of the cornea. The condition is most common in white women over the age of 60.

Symptoms

The most common complaints in Salzmann’s nodular degeneration are reduced visual acuity, excessive tears, photosensitivity and a sensation of sand grit. However, the condition can also be asymptomatic. It shows up as greyish-white to bluish thickening at the front of the cornea.

Causes

To date, no clear cause for this condition has been described. Chronic corneal diseases could increase the risk of Salzmann’s nodules. It often co-occurs with chronic dry eye, chronic blepharitis, trichiasis (eyelashes growing towards the eye), and previous eye trauma and surgery. Still, it seems to occur without such a history in many cases.  There may also be a hereditary factor, and there seems to be a connection with Crohn’s disease.

 

Examination

The eye and the cornea are first examined in detail to make a proper diagnosis and draw up a treatment plan. In addition to the standard examinations, the following ones are specifically important in the case of Salzmann’s nodular degeneration:

  • Eye measurement and visual acuity measurement
  • Split-lamp examination
  • Corneal tomography

Treatment

Eye drops

When the eye feels uncomfortable, eye drops may be prescribed. The eye drops moisturise the eye. They can be used throughout the day.

Surgical treatment

If you experience reduced vision, a phototherapeutic keratectomy may be considered.

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